Anti-MTHFD1L antibodies are used in the immunodetection of the protein methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. In humans, the canonical protein has a reported length of 978 amino acid residues and a mass of 105.8 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is notably expressed in most tissues, highest expression found in the placenta, thymus and brain. A member of the Tetrahydrofolate dehydrogenase/cyclohydrolase protein family; Formate--tetrahydrofolate ligase protein family, MTHFD1L is believed to provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2. Synonyms for this target antigen include MTC1THFS, dJ292B18.2, monofunctional C1-tetrahydrofolate synthase, mitochondrial, 10-formyl-THF synthetase, formyltetrahydrofolate synthetase domain containing 1, and FTHFSDC1. A number of MTHFD1L antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.