Anti-synaptophysin like 1 antibodies are used in the immunodetection of the protein encoded by the SYPL1 gene. In humans, the canonical protein has a reported length of 259 amino acid residues and a mass of 28.6 kDa. Its subcellular localization is in the cytoplasmic vesicles. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Synaptophysin/synaptobrevin protein family, it is known to be involved with chemical synaptic transmission. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include SYPL, synaptophysin-like protein 1, pantophysin, and H-SP1.