Anti-SIT1 antibodies are used in the immunodetection of the protein signaling threshold regulating transmembrane adaptor 1. In humans, the canonical protein has a reported length of 196 amino acid residues and a mass of 21.1 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in T- and B-cells. SIT1 is known to be involved with adaptive immune responses and signal transduction pathways. Post-translational modifications have been described, including phosphorylation and glycosylation. Synonyms for this target antigen include SIT-R, signaling threshold-regulating transmembrane adapter 1, SHP-2 interacting transmembrane adaptor protein, SHP2 interacting transmembrane adaptor, and SIT. SIT1 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of SIT1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Flow Cytometry is also a common application.