Anti-TMEM53 antibodies are used in the immunodetection of the protein transmembrane protein 53. In humans, the canonical protein has a reported length of 277 amino acid residues and a mass of 31.6 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TMEM53 protein family, TMEM53 is known to be involved with the regulation of cell differentiation. The TMEM53 gene has been associated with the disease, Craniotubular dysplasia. Synonyms for this target antigen include novel DUF829 domain-containing protein and nuclear envelope transmembrane protein 4. TMEM53 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. ELISA is the most common application for the TMEM53 antibodies listed below. Western Blot and Immunohistochemistry are also common applications.