Anti-supervillin antibodies are used for the immunodetection of the protein encoded by the SVIL gene. In humans, the canonical protein has a reported length of 2214 amino acid residues and a mass of 247.7 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in many tissues. A member of the Villin/gelsolin protein family, it is known to be involved with cell division and skeletal muscle tissue development. The gene encoding this protein is implicated in Myopathy. Other names for this target antigen include archvillin, membrane-associated F-actin binding protein p205, p205/p250, and MFM10. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chicken species. A number of supervillin antibodies have been mentioned in research publications and have associated citations. Western Blot, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.