Anti-SCUBE1 antibodies are used in the immunodetection of the protein signal peptide, CUB domain and EGF like domain containing 1. In humans, the canonical protein has a reported length of 988 amino acid residues and a mass of 107.9 kDa. Its subcellular localization is in the cell membrane and is secreted. It is notably expressed in endothelial cells. SCUBE1 is known to be involved with endothelial cell differentiation and inflammatory response pathways. Post-translational modifications have been described, including N-glycosylation and protein cleavage. Synonyms for this target antigen include signal peptide, CUB domain, EGF-like 1, signal peptide-CUB domain-EGF-related 1, and signal peptide, CUB and EGF-like domain-containing protein 1. SCUBE1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some SCUBE1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, and Immunofluorescence are also common applications.