Anti-STOM antibodies are used in the immunodetection of the protein stomatin. In humans, the canonical protein has a reported length of 288 amino acid residues and a mass of 31.7 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in erythrocytes. A member of the Band 7/mec-2 protein family, STOM is reported to regulate ion channel activity and transmembrane ion transport.
The STOM marker can be used to identify Myelocytes.* Synonyms for this target antigen include EPB7, EPB72, erythrocyte band 7 integral membrane protein, erythrocyte membrane protein band 7.2 (stomatin), erythrocyte surface protein band 7.2, and BND7. STOM gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of STOM antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4