Anti-SGCZ antibodies are used in the immunodetection of the protein sarcoglycan zeta. In humans, the canonical protein has a reported length of 299 amino acid residues and a mass of 32.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. A member of the Sarcoglycan beta/delta/gamma/zeta protein family, SGCZ is a known component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include zeta-sarcoglycan and zeta-SG. SGCZ gene orthologs have been reported in the mouse, rat, frog, zebrafish, chimpanzee and chicken species. These SGCZ antibodies are widely used in Western Blot experiments, among other applications.