Anti-TTF2 antibodies are used in the immunodetection of the protein transcription termination factor 2. In humans, the canonical protein has a reported length of 1162 amino acid residues and a mass of 129.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the SNF2/RAD54 helicase protein family, TTF2 is reported to be a DsDNA-dependent ATPase, which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. Synonyms for this target antigen include HuF2, ZGRF6, RNA polymerase II termination factor, human factor 2, lodestar homolog, and F2. TTF2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TTF2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.