Anti-TTC3 antibodies are used in the immunodetection of the protein tetratricopeptide repeat domain 3. In humans, the canonical protein has a reported length of 2025 amino acid residues and a mass of 229.9 kDa. Its subcellular localization is in the nucleus, Golgi, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be found in all tissues examined. Post-translational modifications have been described, including protein cleavage and phosphorylation. Synonyms for this target antigen include RNF105, TPRDIII, E3 ubiquitin-protein ligase TTC3, RING finger protein 105, RING-type E3 ubiquitin transferase TTC3, and DCRR1. TTC3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. These TTC3 antibodies are widely used in Western Blot experiments, among other applications.