Anti-TMTC3 antibodies are used in the immunodetection of the protein transmembrane O-mannosyltransferase targeting cadherins 3. In humans, the canonical protein has a reported length of 915 amino acid residues and a mass of 104 kDa. Its subcellular localization is in the ER and membrane. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. It is a member of the TMTC protein family. Post-translational modifications have been described, including glycosylation. The TMTC3 gene has been associated with the disease, Lissencephaly. Synonyms for this target antigen include transmembrane and TPR repeat-containing protein 3, transmembrane and tetratricopeptide repeat containing 3, and protein O-mannosyl-transferase TMTC3. TMTC3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TMTC3 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.