Anti-MPI antibodies are used in the immunodetection of the protein mannose phosphate isomerase. In humans, the canonical protein has a reported length of 423 amino acid residues and a mass of 46.7 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in all tissues, but more abundant in the heart, brain and skeletal muscle. A member of the Mannose-6-phosphate isomerase type 1 protein family, MPI is reported to be involved in synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. Synonyms for this target antigen include PMI, PMI1, mannose-6-phosphate isomerase, phosphohexomutase, phosphomannose isomerase 1, and CDG1B. MPI gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of MPI antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.