Anti-ASCL3 antibodies are used in the immunodetection of the protein achaete-scute family bHLH transcription factor 3. In humans, the canonical protein has a reported length of 180 amino acid residues and a mass of 20.8 kDa. Its subcellular localization is in the nucleus. It is found to be widely expressed in fetal and adult tissues. ASCL3 is known to be a type of transcriptional repressor. The ASCL3 marker can be used to identify Pulmonary Ionocytes.* Synonyms for this target antigen include achaete-scute complex homolog 3, bHLH transcription factor Sgn-1 (Salivary Glands 1), bHLH transcriptional regulator Sgn-1, class A basic helix-loop-helix protein 42, and achaete-scute homolog 3. ASCL3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some ASCL3 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.
*HuBMAP Human Reference Atlas v1.4