Anti-RYR3 antibodies are used in the immunodetection of the protein ryanodine receptor 3. In humans, the canonical protein has a reported length of 4870 amino acid residues and a mass of 552 kDa. Up to 3 different isoforms have been reported for this protein. A member of the Ryanodine receptor (TC 1.A.3.1) protein family, RYR3 is reported to be a calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. Synonyms for this target antigen include brain ryanodine receptor-calcium release channel, brain-type ryanodine receptor, type 3 ryanodine receptor, and CMYP20. RYR3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of RYR3 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.