Anti-RNF19B antibodies are used in the immunodetection of the protein ring finger protein 19B. In humans, the canonical protein has a reported length of 732 amino acid residues and a mass of 77.9 kDa. Its subcellular localization is in the ER and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably expressed in natural killer cells, activated macrophages and cytotoxic T-cells. A member of the RBR protein family, RNF19B is known to be involved with adaptive immune responses and protein ubiquitination. Synonyms for this target antigen include IBR domain-containing protein 3, natural killer lytic-associated molecule, and E3 ubiquitin-protein ligase RNF19B. RNF19B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is a widely used application for the RNF19B antibodies listed below. In addition, Immunofluorescence is also a common application.