Anti-HMGN2 antibodies are used in the immunodetection of the protein high mobility group nucleosomal binding domain 2. In humans, the canonical protein has a reported length of 90 amino acid residues and a mass of 9.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably widely expressed in many tissue types. A member of the HMGN protein family, HMGN2 is known to bind to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. Synonyms for this target antigen include non-histone chromosomal protein HMG-17, high mobility group nucleosome-binding domain-containing protein 2, high mobility group protein N2, and HMG17. HMGN2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HMGN2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.