Anti-OTOA antibodies are used in the immunodetection of the protein otoancorin. In humans, the canonical protein has a reported length of 1153 amino acid residues and a mass of 128.5 kDa. Its subcellular localization is in the extracellular matrix and cell membrane. Up to 5 different isoforms have been reported for this protein. It is notably expressed in the spleen. A member of the Stereocilin protein family, OTOA is believed to act as an adhesion molecule. Post-translational modifications have been described, including glycosylation. The OTOA gene has been associated with the disease, Deafness. Synonyms for this target antigen include cancer/testis antigen 108. OTOA gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Immunohistochemistry is the most common application for the OTOA antibodies listed below. Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.