Anti-PEX6 antibodies are used in the immunodetection of the protein peroxisomal biogenesis factor 6. In humans, the canonical protein has a reported length of 980 amino acid residues and a mass of 104.1 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the retina, at higher levels in the photoreceptor layer at the joint between the outer and inner segments. A member of the AAA ATPase protein family, PEX6 is a known component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Synonyms for this target antigen include PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, peroxisome biogenesis factor 6, peroxin-6, and HMLR2. PEX6 gene orthologs have been reported in the mouse, rat, frog, zebrafish, chimpanzee and chicken species. Some PEX6 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.