Anti-paraoxonase 1 antibodies are used for the immunodetection of the protein encoded by the PON1 gene. In humans, the canonical protein has a reported length of 355 amino acid residues and a mass of 39.7 kDa. It is known to be a secreted protein. A member of the Paraoxonase protein family, it is known to be involved with cholesterol metabolism and homeostasis. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Microvascular complications of diabetes. Other names for this target antigen include MVCD5, PON, serum paraoxonase/arylesterase 1, A-esterase 1, K-45, aromatic esterase 1, arylesterase 1, and ESA. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. A number of paraoxonase 1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.