Anti-KRT10 antibodies are used in the immunodetection of the protein keratin 10. In humans, the canonical protein has a reported length of 584 amino acid residues and a mass of 58.8 kDa. Its subcellular localization is in the cytoplasm and is secreted. It is notably expressed in the skin. A member of the Intermediate filament protein family, KRT10 is reported to play a role in the establishment of the epidermal barrier on plantar skin (By similarity). The KRT10 marker can be used to identify Granular Keratinocytes, Spinous Keratinocytes, and Onychocyte Keratinocytes.* Synonyms for this target antigen include BIE, CK10, EHK, EHK2, IHL, K10, KPP, and BCIE. KRT10 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Over 1300 citations in the literature describe the use of KRT10 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Flow Cytometry, Western Blot, and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4