Anti-PCOLCE2 antibodies are used in the immunodetection of the protein procollagen C-endopeptidase enhancer 2. In humans, the canonical protein has a reported length of 415 amino acid residues and a mass of 45.7 kDa. It has been described to be a secreted protein. It is reported to be highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. PCOLCE2 is known to bind to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1. Post-translational modifications have been described, including O-glycosylation. Synonyms for this target antigen include procollagen C-proteinase enhancer 2, procollagen COOH-terminal proteinase enhancer 2, and PCPE2. PCOLCE2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PCOLCE2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.