Anti-MBD2 antibodies are used in the immunodetection of the protein methyl-CpG binding domain protein 2. In humans, the canonical protein has a reported length of 411 amino acid residues and a mass of 43.3 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the brain, heart, kidney, stomach, testis and placenta. MBD2 is known to bind CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Synonyms for this target antigen include NY-CO-41, demethylase, and DMTase. MBD2 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. A number of MBD2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.