Anti-PARL antibodies are used in the immunodetection of the protein presenilin associated rhomboid like. In humans, the canonical protein has a reported length of 379 amino acid residues and a mass of 42.2 kDa. Its subcellular localization is in the nucleus and mitochondria. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Peptidase S54 protein family, PARL is known to be required for the control of apoptosis during postnatal growth. Post-translational modifications have been described, including protein cleavage and phosphorylation. Synonyms for this target antigen include mitochondrial intramembrane-cleaving protease PARL, rhomboid 7 homolog 1, and presenilins-associated rhomboid-like protein, mitochondrial. PARL gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PARL antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.