Anti-EDC3 antibodies are used in the immunodetection of the protein enhancer of mRNA decapping 3. In humans, the canonical protein has a reported length of 508 amino acid residues and a mass of 56.1 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis. A member of a the EDC3 protein family, EDC3 is known to bind single-stranded RNA. Synonyms for this target antigen include LSM16 homolog (EDC3, S. cerevisiae), enhancer of mRNA decapping 3 homolog, yjeF N-terminal domain-containing protein 2, yjeF domain containing, and enhancer of mRNA-decapping protein 3.