Anti-major vault protein antibodies are used for the immunodetection of the protein encoded by the MVP gene. In humans, the canonical protein has a reported length of 893 amino acid residues and a mass of 99.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be required for normal vault structure. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include VAULT1, lung resistance-related protein, testicular secretory protein Li 30, and LRP. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 50 citations in the literature describe the use of major vault protein antibodies in research. Immunohistochemistry is a widely used application for these antibodies. Flow Cytometry, Western Blot, and Immunofluorescence are also common applications.