Anti-GPR22 antibodies are used in the immunodetection of the protein G protein-coupled receptor 22. In humans, the canonical protein has a reported length of 433 amino acid residues and a mass of 49.3 kDa. Its subcellular localization is in the cell membrane. It is reported be highly expressed in adult and fetal heart tissue. A member of the G-protein coupled receptor 1 protein family, it is known to be involved with GPCR signaling pathways. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include probable G-protein coupled receptor 22.