Anti-CIB2 antibodies are used in the immunodetection of the protein calcium and integrin binding family member 2. In humans, the canonical protein has a reported length of 187 amino acid residues and a mass of 21.6 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is widely expressed across many tissue types. CIB2 is known to be involved with the regulation of intracellular calcium. The CIB2 marker can be used to identify Neuro-Medullary Thymic Epithelial Cells.* Synonyms for this target antigen include KIP2, USH1J, DNA-dependent protein kinase catalytic subunit-interacting protein 2, and DFNB48. CIB2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4