Anti-LDHD antibodies are used in the immunodetection of the protein lactate dehydrogenase D. In humans, the canonical protein has a reported length of 507 amino acid residues and a mass of 54.9 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is noted to be expressed moderately in the heart and liver and at lower levels in skeletal muscle and kidney. A member of the FAD-binding oxidoreductase/transferase type 4 protein family, LDHD is known to be involved in D-lactate, but not L-lactate catabolic process. The LDHD gene has been associated with the disease, D-lactic aciduria with gout. Synonyms for this target antigen include probable D-lactate dehydrogenase, mitochondrial and D-lactate dehydrogenase. LDHD gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the LDHD antibodies listed below. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.