Anti-KLF6 antibodies are used in the immunodetection of the protein KLF transcription factor 6. In humans, the canonical protein has a reported length of 283 amino acid residues and a mass of 31.9 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the placenta followed by spleen, thymus, prostate, testis, small intestine and colon. A member of the Krueppel C2H2-type zinc-finger protein family, KLF6 is known to be involved with B cell differentiation and the regulation of transcription.
The KLF6 marker can be used to identify Follicular Dendritic Cells (FDC).* Synonyms for this target antigen include CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9, and BCD1. KLF6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of KLF6 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4