Anti-MBD4 antibodies are used in the immunodetection of the protein methyl-CpG binding domain 4, DNA glycosylase. In humans, the canonical protein has a reported length of 580 amino acid residues and a mass of 66.1 kDa. Its subcellular localization is in the nucleus. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. MBD4 is known to be involved with DNA repair. The MBD4 gene has been associated with the disease, Tumor predisposition syndrome. Synonyms for this target antigen include TPDS2, UVM1, methyl-CpG-binding domain protein 4, 3,N(4)-ethenocytosine glycosylase, G/5-fluorouracil mismatch glycosylase with biphasic kinetics, and MED1. MBD4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of MBD4 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.