Anti-INVS antibodies are used in the immunodetection of the protein inversin. In humans, the canonical protein has a reported length of 1065 amino acid residues and a mass of 117.8 kDa. Its subcellular localization is in the membrane, nucleus, and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. INVS is reported to be required for normal renal development and establishment of left-right axis. Post-translational modifications have been described, including ubiquitination. The INVS gene has been associated with the disease, Nephronophthisis. Synonyms for this target antigen include INV and NPH2. INVS gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the INVS antibodies listed below. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.