Anti-CCDC65 antibodies are used in the immunodetection of the protein coiled-coil domain containing 65. In humans, the canonical protein has a reported length of 484 amino acid residues and a mass of 57.3 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in adult testis, in spermatocytes and spermatids. A member of the DRC2 protein family, CCDC65 is a known component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Synonyms for this target antigen include dynein regulatory complex subunit 2 and testis development protein NYD-SP28. CCDC65 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some CCDC65 antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.