Anti-COPB2 antibodies are used in the immunodetection of the protein COPI coat complex subunit beta 2. In humans, the canonical protein has a reported length of 906 amino acid residues and a mass of 102.5 kDa. Its subcellular localization is in the membrane, cytoplasmic vesicles, Golgi, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the WD repeat COPB2 protein family, COPB2 is known to be involved with Golgi transport and intracellular protein transport. The COPB2 gene has been associated with the disease, Microcephaly. Synonyms for this target antigen include OPDD, beta'-COP, coatomer subunit beta', beta'-coat protein, betaprime-COP, and MCPH19. COPB2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of COPB2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.