Anti-PLCZ1 antibodies are used in the immunodetection of the protein phospholipase C zeta 1. In humans, the canonical protein has a reported length of 608 amino acid residues and a mass of 70.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the testis and sperm. PLCZ1 is known to be involved with the transport of ions and intracellular signal transduction. The PLCZ1 gene has been associated with the disease, Spermatogenic failure. Synonyms for this target antigen include PI-phospholipase C zeta 1, phosphoinositide phospholipase C-zeta-1, testicular tissue protein Li 145, and 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1. PLCZ1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some PLCZ1 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.