Anti-hippocalcin antibodies are used for the immunodetection of the protein encoded by the HPCA gene. In humans, the canonical protein has a reported length of 193 amino acid residues and a mass of 22.4 kDa. Its subcellular localization is in the membrane and cytoplasm. It is reported to have brain specific expression. A member of the Recoverin protein family, it is reported to be a calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. Other names for this target antigen include DYT2, neuron-specific calcium-binding protein hippocalcin, calcium-binding protein BDR-2, dystonia 2, torsion (autosomal recessive), and BDR2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some hippocalcin antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.