Anti-ATP8A2 antibodies are used in the immunodetection of the protein ATPase phospholipid transporting 8A2. In humans, the canonical protein has a reported length of 1188 amino acid residues and a mass of 133.6 kDa. Its subcellular localization is in the Golgi and cell membrane. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the brain, cerebellum, retina and testis. A member of the Cation transport ATPase (P-type) (TC 3.A.3) protein family, ATP8A2 is reported to be a catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids (By similarity). Synonyms for this target antigen include ATPIB, CAMRQ4, IB, ML-1, phospholipid-transporting ATPase IB, and ATP. ATP8A2 gene orthologs have been reported in the mouse, rat, frog, zebrafish, chimpanzee and chicken species. ELISA is the most common application for the ATP8A2 antibodies listed below. Flow Cytometry and Western Blot are also common applications.