Anti-ANO3 antibodies are used in the immunodetection of the protein anoctamin 3. In humans, the canonical protein has a reported length of 981 amino acid residues and a mass of 114.7 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the forebrain striatum. A member of the Anoctamin protein family, ANO3 is known to have calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (By similarity). Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include dystonia 23 and transmembrane protein 16C (eight membrane-spanning domains). ANO3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ANO3 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.