Anti-ADCY1 antibodies are used in the immunodetection of the protein adenylate cyclase 1. In humans, the canonical protein has a reported length of 1119 amino acid residues and a mass of 123.4 kDa. Its subcellular localization is in the cell membrane and cytoplasm. It is notably expressed in zona glomerulosa and zona fasciculata in the adrenal gland. A member of the Adenylyl cyclase class-4/guanylyl cyclase protein family, ADCY1 is known to catalyze the formation of the signaling molecule cAMP in response to G-protein signaling. Synonyms for this target antigen include DFNB44, adenylate cyclase type 1, 3',5'-cyclic AMP synthetase, ATP pyrophosphate-lyase 1, Ca(2+)/calmodulin-activated adenylyl cyclase, and AC1. ADCY1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of ADCY1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.