Anti-ADAMTSL1 antibodies are used in the immunodetection of the protein ADAMTS like 1. In humans, the canonical protein has a reported length of 1762 amino acid residues and a mass of 193.4 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Up to 6 different isoforms have been reported for this protein. It is notably expressed in adult skeletal muscle. ADAMTSL1 is known to be involved with extracellular matrix organization. Post-translational modifications have been described, including O-glycosylation and N-glycosylation.
The ADAMTSL1 marker can be used to identify Deep-Layer Corticothalamic And 6B Neurons, Eccentric Medium Spiny Neurons, Cerebral Cortex MGE Interneurons, and Medulla Oblongata Splatter Neurons.* Synonyms for this target antigen include ADAM-TS related protein 1, punctin-1, and ADAMTS-like protein 1. ADAMTSL1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some ADAMTSL1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4