Anti-CLIC2 antibodies are used in the immunodetection of the protein chloride intracellular channel 2. In humans, the canonical protein has a reported length of 247 amino acid residues and a mass of 28.4 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. A member of the Chloride channel CLIC protein family, CLIC2 is known to be involved with signal transduction pathways. The CLIC2 gene has been associated with the disease, Intellectual developmental disorder. Synonyms for this target antigen include CLIC2b, MRXS32, XAP121, chloride intracellular channel protein 2, and CLCNL2. CLIC2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish and chimpanzee species. Some CLIC2 antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.