Anti-CHP2 antibodies are used in the immunodetection of the protein calcineurin like EF-hand protein 2. In humans, the canonical protein has a reported length of 196 amino acid residues and a mass of 22.5 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. It is reported to be expressed in malignantly transformed cells but not detected in normal tissues. A member of the Calcineurin regulatory subunit protein family, CHP2 is known to function as a integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Synonyms for this target antigen include hepatocellular carcinoma antigen gene 520, hepatocellular carcinoma-associated antigen 520, and calcineurin B homologous protein 2. CHP2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Some CHP2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.