Anti-ASTL antibodies are used in the immunodetection of the protein astacin like metalloendopeptidase. In humans, the canonical protein has a reported length of 431 amino acid residues and a mass of 45.9 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, and cytoplasm. ASTL is known to be involved with cell adhesion and proteolysis. The ASTL gene has been associated with the disease, Oocyte maturation defect. Synonyms for this target antigen include astacin-like metallo-endopeptidase (M12 family), astacin-like metalloendopeptidase (M12 family), oocyte astacin, ovastacin, sperm acrosomal SLLP1 binding, and ZP2-proteinase. ASTL gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species.