Anti-ADRA2B antibodies are used in the immunodetection of the protein adrenoceptor alpha 2B. In humans, the canonical protein has a reported length of 450 amino acid residues and a mass of 50 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the testis, soft tissue, and cerebellum. A member of the G-protein coupled receptor 1 protein family, ADRA2B is known to be involved with angiogenesis and cell to cell signaling. The ADRA2B gene has been associated with the disease, Epilepsy. Synonyms for this target antigen include ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR, and ADRA2L1. ADRA2B gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.