Anti-CLN3 antibodies are used in the immunodetection of the protein CLN3 lysosomal/endosomal transmembrane protein, battenin. In humans, the canonical protein has a reported length of 438 amino acid residues and a mass of 47.6 kDa. Up to 7 different isoforms have been reported for this protein. It is reported to be expressed in the cortical brain, pancreas, spleen, and testis with weaker expression in the peripheral nerve. A member of the Battenin protein family, CLN3 is known to mediate microtubule-dependent, anterograde transport connecting the Golgi network, endosomes, autophagosomes, lysosomes and plasma membrane, and participates in several cellular processes such as regulation of lysosomal pH, lysosome protein degradation, receptor-mediated endocytosis, autophagy, transport of proteins and lipids from the TGN, apoptosis and synaptic transmission. Synonyms for this target antigen include BTS, JNCL, battenin, CLN3, battenin, batten disease protein, ceroid-lipofuscinosis, neuronal 3, and BTN1. Some CLN3 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.