Anti-CHMP4B antibodies are used in the immunodetection of the protein charged multivesicular body protein 4B. In humans, the canonical protein has a reported length of 224 amino acid residues and a mass of 25 kDa. Its subcellular localization is in the membrane, nucleus, and cytoplasm. It is widely expressed across many tissue types. A member of the SNF7 protein family, CHMP4B is a suspected core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The CHMP4B gene has been associated with the disease, Cataracts. Synonyms for this target antigen include Snf7 homologue associated with Alix 1, chromatin modifying protein 4B, chromatin-modifying protein 4b, vacuolar protein-sorting-associated protein 32-2, and SNF7 homolog associated with Alix 1. A number of CHMP4B antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.