Anti-ACER3 antibodies are used in the immunodetection of the protein alkaline ceramidase 3. In humans, the canonical protein has a reported length of 267 amino acid residues and a mass of 31.6 kDa. Its subcellular localization is in the ER and Golgi. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the Alkaline ceramidase protein family, ACER3 is known to be involved with inflammatory response pathways and the regulation of cell proliferation. The ACER3 gene has been associated with the disease, Leukodystrophy. Synonyms for this target antigen include PHCA, PLDECO, alkCDase 3, alkaline CDase 3, alkaline dihydroceramidase SB89, and APHC. ACER3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the ACER3 antibodies listed below. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.