Anti-TOPORS antibodies are used in the immunodetection of the protein TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase. In humans, the canonical protein has a reported length of 1045 amino acid residues and a mass of 119.2 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. TOPORS is known to function as a E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Post-translational modifications have been described, including ubiquitination, sumoylation and phosphorylation. Synonyms for this target antigen include P53BP3, RP31, TP53BPL, E3 ubiquitin-protein ligase Topors, RING-type E3 ubiquitin transferase Topors, and LUN. TOPORS gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some TOPORS antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.