Anti-PIP5K1B antibodies are used in the immunodetection of the protein phosphatidylinositol-4-phosphate 5-kinase type 1 beta. In humans, the canonical protein has a reported length of 540 amino acid residues and a mass of 61 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in fetal pancreas, brain, kidney, skeletal muscle and lung. PIP5K1B is known to catalyze the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity). Synonyms for this target antigen include STM7, PIP5K1-beta, PIP5KIbeta, phosphatidylinositol 4-phosphate 5-kinase type I beta, protein STM-7, and MSS4. A number of PIP5K1B antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.