Anti-IGHA1 antibodies are used in the immunodetection of the protein immunoglobulin heavy constant alpha 1. In humans, the canonical protein has a reported length of 398 amino acid residues and a mass of 42.8 kDa. Its subcellular localization is in the cell membrane and is secreted. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as in adipose tissue and breast. IGHA1 is known to be involved with adaptive immune responses. Post-translational modifications have been described, including O-glycosylation. The IGHA1 marker can be used to identify Memory B Cells.*
*HuBMAP Human Reference Atlas v1.4