Anti-HERC4 antibodies are used in the immunodetection of the protein HECT and RLD domain containing E3 ubiquitin protein ligase 4. In humans, the canonical protein has a reported length of 1057 amino acid residues and a mass of 118.6 kDa. Its subcellular localization is in the cytoplasm. Up to 6 different isoforms have been reported for this protein. It is reported to be expressed in the brain and testis and detected in the heart and placenta. HERC4 is a suspected E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Synonyms for this target antigen include HECT domain and RCC1-like domain-containing protein 4, HECT-type E3 ubiquitin transferase HERC4, hect domain and RLD 4, and probable E3 ubiquitin-protein ligase HERC4. HERC4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some HERC4 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunofluorescence is also a common application.